Excel Enthalpy Change: Thermodynamic Analysis

How To Calculate Enthalpy Change?

However, the first thing you need is data that looks like this:

Click on an empty cell (1), and type in the formula

=(C4*B4) + B5*(C5+C6*B6) (2), and press enter.

Enthalpy change has been calculated.

Template

Further reading: 
Basic concepts 
Getting started with Excel
Cell References